Nuclear Receptors as Nutriable Targets
Title
Nuclear Receptors as Nutriable Targets
Abstract
A druggable target, or more appropriately a druggable domain, is a functional region of a protein for which a significant fraction of family members have been successfully targeted by drugs. What makes the protein druggable is the fact that a domain on this protein responds to small chemicals including intracellular metabolites, xenobiotics such as drugs as well as dietary agents. Thus a druggable target is responsive to components of the diet and hence nutriable. Nutriable targets include GPCR, nuclear receptors and various kinase families.
Nuclear Receptor Resource; NRResource.org
