Human Retinoic Acid Receptor Gamma
(RARg; NR1B3)
Family of Reporter Assay Systems

The Human RARg Reporter Assay Systems utilize non-human mammalian cells engineered to provide constitutive, high-level expression of Human Retinoic Acid Receptor Gamma (NR1B3), a ligand-dependent transcription factor commonly referred to as RARg. Additionally, these cells contain a RARg-responsive luciferase reporter gene. Thus, quantifying luciferase activity provides a surrogate measure of RARg activity in the treated reporter cells.