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INDIGO Biosciences Launches Retinoic Acid Receptor (RAR) Gamma Assay System

November 29, 2010- State College, PA INDIGO Biosciences, The Nuclear Receptor Company, announces the addition of another product to its growing line of INDIGO Nuclear Receptor Assay Kits. The INDIGO RARγ Assay Kits are a robust, easy-to-use, high and low throughput screening solution for researchers in drug discovery and development research and toxicology studies.

Retinoic Acid Receptor Gamma (RARγ) is a nuclear hormone receptor that binds hormones derived from retinol (vitamin A) and regulates gene expression, impacting a wide range of biological processes. “The number of diseases affected by this nuclear receptor is fascinating,” says Jack Vanden Heuvel, PhD, Chief Science Officer of INDIGO Biosciences. “Several current acne treatments use RAR activators as a key ingredient. Recent studies have indicated that RARγ may play a role in neurodegenerative diseases, schizophrenia, and other psychiatric disorders. Obviously, having a selective and robust RARγ assay will be of interest to many scientists working on a wide range of diseases and conditions.” The INDIGO RARγ Assay Kits are a valuable asset for researchers conducting small-molecule screening studies of compounds that could potentially affect these diseases.

The INDIGO RARγ Assay Kits are essentially an all-inclusive lab-in-a-box that enables researchers to go from freezer to data in 24 hours in four easy steps: Thaw, Feed, Dose, Read. Cumbersome, time-consuming cell counting and washing steps are unnecessary with all INDIGO Nuclear Receptor Assay Kits, setting a new standard for convenience and efficacy.

The INDIGO RARγ Assay Kits are highly reliable. They use stable-glow luciferase chemistry to produce results with excellent Z’ scores and high signal-to-noise ratios. INDIGO Biosciences’ proprietary cryopreservation process, CryoMite, has 95% cell viability post-thaw and enables INDIGO Nuclear Receptor Assay Kits to be shipped anywhere in the United States overnight, making them ready to use when the researcher is ready to test.

For more information about INDIGO Nuclear Receptor Assay Kits or the proprietary CryoMiteTM technology, please contact Mark Capriani, Vice President of Sales & Marketing at INDIGO Biosciences, Inc. by calling (814) 234-1919 or by e-mailing to mark@indigobiosciences.com. You may also visit INDIGO Biosciences, Inc. on the worldwide web at www.indigobiosciences.com.