| Entities | Apoca ---- THRB |
|---|---|
| References | 1 |
| Connectivity | 2 |
| Effect | unknown |
| Owner | Public |
| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:7068:inout-urn:agi-llid:117587::unknown |
| Tissue | thyroid |
|---|---|
| MedLine Reference | 12585964:5 |
| Sentence | Transactivation of the HCR-1/apoC-II promoter cluster by RXRalpha-FXRalpha heterodimers in the presence of CDCA was abolished by mutations either in the IR-1 HRE of the HCR-1 or in the thyroid HRE of the proximal apoC-II promoter, which binds RXRalpha-thyroid hormone receptor beta (T3Rbeta) heterodimers. |