Expression :

Owner Public
URN urn:agi-Expression:inout-urn:agi-cas:6893-02-3:out-urn:agi-llid:7067::negative
Entities T3 ---| THRA
References 3
Connectivity 2
Effect negative

Organism Rattus norvegicus
Journal Endocrin. Metabol
Journal Reference v286 i6 pE968 (2004)
Journal Link http://ajpendo.physiology.org/cgi/content/full/286/6/E968
Organ liver
MedLine Reference 14970006:1208
Sentence Recent studies have reported decreases or no effect of T3 on TRalpha1 mRNA expression ( 16 ).

Organism Mus musculus
CellLineName Neuro 2A
MedLine Reference 8146169:4
Sentence T3 had no effect on the differentiation of Neuro-2a cells that overexpressed TR alpha 1.

CellLineName GC
Journal PNAS
Journal Reference v97 i16 p8985 (2000)
Journal Link http://www.pnas.org/cgi/content/full/97/16/8985
MedLine Reference 10908671:1021
Sentence T3 also induced rapid degradation of TReta2 and TRalpha1.