| Owner | Public |
|---|---|
| URN | urn:agi-DirectRegulation:inout-urn:agi-llid:9611:out-urn:agi-llid:7068::unknown |
| Entities | THRB <--- NCOR1 |
| References | 5 |
| Effect | unknown |
| Connectivity | 2 |
| MedLine Reference | 12089344:5 |
|---|---|
| Sentence | In support of this hypothesis it was demonstrated that the presence of N-CoR can enhance TRbeta-mediated transcriptional activation. |
| MedLine Reference | 9449636:1111 |
|---|---|
| Sentence | The TRbeta homodimer complex was dissociated by the addition of 20 n M T3 and also prevented the formation of the TRbeta complex with NCoR-ID (Fig. 2B , lane 4). |
| CellType | reticulocyte |
| Journal | Endocrinology |
| Journal Reference | v139 i2 p640 (1998) |
| Journal Link | http://endo.endojournals.org/cgi/content/full/139/2/640 |
| MedLine Reference | 9751500:1013 |
|---|---|
| Sentence | In electrophoretic mobility shift assays, wild-type TRbeta-1 interacted with N-CoR in the absence of ligand, whereas T3 caused dissociation of the TRbeta-1/N-CoR complex and formation of TRbeta-1/SRC-1 complex. |
| Tissue | thyroid |
| Journal | Endocrinology |
| Journal Reference | v139 i10 p4197 (1998) |
| Journal Link | http://endo.endojournals.org/cgi/content/full/139/10/4197 |
| MedLine Reference | 11435607:2 |
|---|---|
| Sentence | We have previously demonstrated that TRbeta1 preferentially interacts with NCoR, whereas RARalpha prefers SMRT. |
| MedLine Reference | 14985366:1176 |
|---|---|
| Sentence | We confirmed interaction between N-CoR and TRbeta1 using GST-pull down studies. |
| Tissue | endocrine |
| Journal | J. Biol. Chem |
| Journal Reference | v279 i18 p18195 (2004) |
| Journal Link | http://www.jbc.org/cgi/content/full/279/18/18195 |