| Name | PLTP |
|---|---|
| Description | phospholipid transfer protein |
| Owner | Public |
| URN | urn:agi-llid:5360 |
| Connectivity | 24 |
| Notes | The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. |
| Hugo ID | 9093 |
| Microarray ID | 1391435_at |
|---|---|
| 1382771_at | |
| rc_ai171583_at | |
| rc_ai230465_at | |
| 100927_at | |
| 1417963_at | |
| 1456424_s_at | |
| 1458466_at | |
| u37226_s_at | |
| A_51_P226655 | |
| 40081_at | |
| 73218_at | |
| 202075_s_at | |
| A_23_P5983 | |
| A_14_P114039 | |
| N076 | |
| OH2801 | |
| MA316 |
| Chromosome position | 3q42 |
|---|---|
| 5q36 | |
| 2 93.0 cM | |
| 20q12-q13.1 | |
| 4 D1 |
| GO ID | 0005576 |
|---|---|
| 0006629 | |
| 0006869 | |
| 0008289 | |
| 0007276 | |
| 0006810 | |
| 0005615 |
| Alias | similar to phospholipid transfer protein |
|---|---|
| Pltp_predicted | |
| Zfp393s | |
| gzf | |
| Doi 561 | |
| AA420409 | |
| hypothetical protein FLJ40160 | |
| C85123 | |
| phospholipid transfer protein | |
| D4Ertd561e | |
| 7420700M05Rik | |
| FLJ40160 | |
| germ cell specific zinc finger protein | |
| zinc finger protein 393 | |
| AU043468 | |
| expressed sequence AU043468 | |
| RIKEN cDNA 7420700M05 gene | |
| Lipid transfer protein II | |
| Zfp393 | |
| Pltp | |
| Doi 561s |
| Organism | Rattus norvegicus |
|---|---|
| Homo sapiens | |
| Mus musculus |
| MedLine Reference | 12351194 |
|---|---|
| 7654777 | |
| 12466851 |
| LocusLink ID | 5360 |
|---|---|
| 18830 | |
| 100330 | |
| 75753 | |
| 52329 | |
| 97176 | |
| 98794 | |
| 298449 | |
| 296371 | |
| 246786 |
| FunctionalClass | lipid binding |
|---|
| RGD ID | 1306695 |
|---|
| Hugo Symbol | PLTP |
|---|
| Unigene ID | Mm.6105 |
|---|---|
| Rn.117434 | |
| Hs.439312 |
| GO Cellular Component | extracellular region |
|---|---|
| extracellular space |
| Cell Localization | Extracellular |
|---|---|
| Cytoplasm |
| Pathway | INS-HLA-DRB1 |
|---|---|
| INS-TFRC | |
| CLA Grow | |
| PPAR all | |
| FXR | |
| PPARalpha | |
| LXR | |
| NR common targets |
| GO Biological Process | lipid metabolism |
|---|---|
| lipid transport | |
| gametogenesis | |
| transport |
| Group | New Group |
|---|---|
| CLA Grow |
| State | isoform a precursor |
|---|---|
| isoform b precursor |
| State Description | Transcript Variant: This variant (1) encodes the predominant isoform (a). |
|---|---|
| Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1, resulting in an isoform (b) which has the same N- and C-termini but which is shorter than isoform a. |
| MGI ID | 103151 |
|---|
| Swiss-Prot Accession | P55058 |
|---|
| OMIM ID | 172425 |
|---|
| Source | Curated |
|---|