| Name | ABCG1 |
|---|---|
| Description | ATP-binding cassette, sub-family G (WHITE), member 1 |
| Owner | Public |
| URN | urn:agi-llid:9619 |
| Connectivity | 9 |
| Notes | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Several alternative splice variants have been identified. Abcg1 is a key gene involved in both cholesterol efflux to HDL and in tissue lipid homeostasis. Analysis of the effect of the Su(Hw) insulator on the expression of the miniwhite gene in Drosophila melanogaster. |
| Microarray ID | 1368103_at |
|---|---|
| 1387054_at | |
| rc_aa944183_at | |
| rc_ai179131_at | |
| A_42_P638318 | |
| 103008_at | |
| 1423570_at | |
| 160612_at | |
| u34920_s_at | |
| A_51_P222467 | |
| 41362_at | |
| 211113_s_at | |
| 204567_s_at | |
| X91249_at | |
| A_23_P166297 | |
| A_14_P116720 | |
| A_14_P121289 | |
| M669 | |
| E199 | |
| OH8448 |
| Chromosome position | 20p12 |
|---|---|
| 21q22.3 | |
| 17 A2-B |
| GO ID | 0042632 |
|---|---|
| 0005615 | |
| 0006810 | |
| 0016021 | |
| 0030301 | |
| 0046983 | |
| 0000166 | |
| 0005524 | |
| 0005624 | |
| 0005783 | |
| 0005795 | |
| 0005887 | |
| 0006869 | |
| 0008203 | |
| 0009720 | |
| 0010033 | |
| 0015196 | |
| 0015216 | |
| 0015646 | |
| 0016020 | |
| 0016887 | |
| 0042626 |
| Alias | Abc8 |
|---|---|
| Abcg1 | |
| ATP-binding cassette 8 | |
| ATP-binding cassette 8 (homolog of Drosophila white) | |
| ATP-binding cassette sub-family G member 1 isoform b | |
| ATP-binding cassette, subfamily G, member 1 | |
| ATP-binding cassette, sub-family G, member 1 | |
| homolog of Drosophila white | |
| White protein homolog | |
| white protein homolog (ATP-binding cassette transporter 8) | |
| WHITE1 | |
| WHT1 | |
| ATP-binding cassette VIII | |
| ABC transporter VIII | |
| ATP-binding cassette transporter VIII | |
| homolog of white | |
| ATP-binding cassette, sub-family G, member I | |
| ABC transporter 8 | |
| ATP-binding cassette transporter 8 | |
| ATP-binding cassette, subfamily G, member I | |
| Abcg I | |
| WHT I | |
| MGC34313 | |
| ATP-binding cassette sub-family G member 1 isoform a | |
| WHITE I | |
| ATP-binding cassette, sub-family G (WHITE), member I | |
| ATP-binding cassette, sub-family G (WHITE), member 1 | |
| WHITE1s | |
| WHITE Is | |
| atp-binding cassette transporter member 1 of subfamily g |
| Organism | Mus musculus |
|---|---|
| Rattus norvegicus | |
| Homo sapiens |
| MedLine Reference | 11500512 |
|---|---|
| 9034316 | |
| 12466851 | |
| 15319426 | |
| 11590207 |
| LocusLink ID | 106791 |
|---|---|
| 9619 | |
| 11307 | |
| 85264 |
| FunctionalClass | ATP binding |
|---|---|
| ATPase | |
| ATPase activity, coupled to transmembrane movement of substances | |
| L-tryptophan transporter | |
| nucleotide binding | |
| permease | |
| protein dimerization | |
| purine nucleotide transporter |
| GO Cellular Component | extracellular space |
|---|---|
| integral to membrane | |
| Golgi stack | |
| endoplasmic reticulum | |
| integral to plasma membrane | |
| membrane | |
| membrane fraction |
| Cell Localization | Plasma membrane |
|---|
| Pathway | LXR |
|---|---|
| NR common targets | |
| NR CYP ABCs | |
| NR target genes |
| GO Biological Process | cholesterol transport |
|---|---|
| transport | |
| cholesterol homeostasis | |
| cholesterol metabolism | |
| detection of hormone stimulus | |
| lipid transport | |
| response to organic substance |
| Group | Transporters |
|---|---|
| ABCs |