| Entities | NR1H3 ---- NR0B2 |
|---|---|
| References | 3 |
| Connectivity | 2 |
| Effect | unknown |
| Owner | Public |
| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:8431:inout-urn:agi-llid:10062::unknown |
| Organ | kidney |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v278 i38 p36418 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/38/36418 |
| MedLine Reference | 12842887:1306 |
| Sentence | Interestingly, the human SHP promoter has also been shown to bind LXR at a DR-4 site, which also overlaps the FXR IR-1 element ( 60 ), in a manner analogous to the ERalpha binding site. |
| Organism | Mus musculus |
| Journal | Mol. Endocrin |
|---|---|
| Journal Reference | v17 i3 p386 (2003) |
| Journal Link | http://mend.endojournals.org/cgi/content/full/17/3/386 |
| MedLine Reference | 12554795:1097 |
| Sentence | The LXRE in the SHP Promoter Binds LXR /RXR Heterodimers A, Sequence of the oligonucleotide probes (sense strand only) corresponding to the previously characterized LXRE in the rat CYP7A1 promoter (CYP7A1 DR4) and the putative LXRE from the hSHP promoter (SHP DR4). |
| Organism | Rattus norvegicus |
| Organ | liver |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v279 i27 p28122 (2004) |
| Journal Link | http://www.jbc.org/cgi/content/full/279/27/28122 |
| MedLine Reference | 15123650:1032 |
| Sentence | More recently, LXRalpha has been shown to induce human but not rat SHP gene expression via direct binding to the LXR response element in human SHP promoter ( 22 ), which in turn represses CYP7A1 gene expression. |
| Organism | Mus musculus |