| Transport Type | unknown |
|---|---|
| Owner | Public |
| URN | urn:agi-MolTransport:inout-urn:agi-llid:10062:out-urn:agi-cas:50-99-7::unknown |
| Entities | glucose <--- NR1H3 |
| References | 4 |
| Connectivity | 2 |
| Effect | unknown |
| Tissue | blood |
|---|---|
| Organism | Mus musculus |
| MedLine Reference | 12923232:1187 |
| Sentence | Because Cao et al. ( 19 ) used peripheral blood for their studies, and it has been recently shown that LXR may upregulate tissue glucose uptake, perhaps the major plasma glucose-lowering effect of LXR ligands results from increased peripheral tissue glucose uptake. |
| Journal | Lipid Res |
| Journal Reference | v44 i11 p2039 (2003) |
| Journal Link | http://www.jlr.org/cgi/content/full/44/11/2039 |
| Organism | Mus musculus |
|---|---|
| MedLine Reference | 12697904:8 |
| CellType | adipocyte |
| Sentence | Consistent with their effects on GLUT4 expression, LXR agonists promote glucose uptake in 3T3-L1 adipocytes in vitro. |
| CellLineName | 3T3 L1 |
| Organism | Mus musculus |
|---|---|
| MedLine Reference | 12138207:1316 |
| CellType | adipocyte |
| Sentence | Taken together, these data suggest that activation of LXR increases glucose uptake and storage, at least in part, due to an increase in GLUT1. |
| Journal | Mol. Cell. Biol |
| Journal Reference | v22 i16 p5989 (2002) |
| Journal Link | http://mcb.asm.org/cgi/content/full/22/16/5989 |
| CellLineName | 3T3 L1 |
| Tissue | fat |
|---|---|
| Organism | Mus musculus |
| MedLine Reference | 12554745:1198 |
| Sentence | These authors rather demonstrated new metabolic roles for LXR in adipose tissue with effects on metabolic pathways such as increased basal glucose uptake, glycogen synthesis, cholesterol synthesis, and release of nonesterified fatty acids. |
| Journal | Mol. Endocrin |
| Journal Reference | v17 i2 p172 (2003) |
| Journal Link | http://mend.endojournals.org/cgi/content/full/17/2/172 |