| Name | IPO8 |
|---|---|
| Description | importin 8 |
| Owner | Public |
| URN | urn:agi-llid:10526 |
| Connectivity | 3 |
| Notes | The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. |
| Microarray ID | 104163_at |
|---|---|
| 1426760_at | |
| 1452185_at | |
| aa416454_rc_s_at | |
| A_51_P465327 | |
| A_51_P234470 | |
| A_52_P462366 | |
| A_51_P234466 | |
| 225528_at | |
| 35123_at | |
| 55735_at | |
| 205701_at | |
| A_23_P98923 | |
| A_14_P133876 | |
| A_14_P116110 | |
| A_14_P100916 | |
| OH4826A | |
| AH1075 |
| Chromosome position | 6 G3 |
|---|---|
| 12p11.21 |
| GO ID | 0000059 |
|---|---|
| 0005488 | |
| 0005634 | |
| 0005643 | |
| 0005737 | |
| 0007165 | |
| 0008536 | |
| 0008565 | |
| 0015031 | |
| 0005887 | |
| 0006810 | |
| 0042626 |
| Alias | OM(1) |
|---|---|
| Om1 | |
| OM-1 | |
| OM 1 | |
| RAN binding protein 8 | |
| 6230418K12Rik | |
| RAN binding protein VIII | |
| importin VIII | |
| IPO8 | |
| oocyte maturation I | |
| C130009K11Rik | |
| importin 8 | |
| RANBP8 | |
| oocyte maturating 1 | |
| oocyte maturating I | |
| oocyte maturation 1 | |
| RANBP8s |
| Organism | Mus musculus |
|---|---|
| Homo sapiens |
| MedLine Reference | 9214382 |
|---|---|
| 11943485 |
| LocusLink ID | 50504 |
|---|---|
| 359801 | |
| 10526 | |
| 320727 |
| FunctionalClass | Ran GTPase binding |
|---|---|
| binding | |
| protein transporter | |
| ATPase activity, coupled to transmembrane movement of substances |
| GO Cellular Component | cytoplasm |
|---|---|
| nuclear pore | |
| nucleus | |
| integral to plasma membrane |
| Cell Localization | Plasma membrane |
|---|
| Pathway | GR |
|---|
| GO Biological Process | protein transport |
|---|---|
| protein-nucleus import, docking | |
| signal transduction | |
| transport |
| Group | Gtp binding proteins |
|---|
| Source | Curated |
|---|