Protein : SCAM-1

Name SCAM-1
Description vinexin beta (SH3-containing adaptor molecule-1)
Owner Public
URN urn:agi-llid:10174
Connectivity 11
Notes Phosphorylation of the AF-1 domain controls RARgamma-mediated transcription through triggering the dissociation of vinexin beta. Regulates cytoskeletal organization and signal transduction--review. Vinexin is a novel substrate of ERK2 and may play roles in ERK-dependent cell regulation.

Microarray ID 136386_at
1419329_at
98848_at
u58889_s_at
A_51_P447795
35675_at
53507_r_at
209253_at
207788_s_at
rc_aa478411_at
A_23_P168892
A_23_P300710
A_14_P139103
A_23_P300714
OH4580

GenBank ID BC030933
NC_000080
AAH83666
AAN63631
AF439378
BC083666
NC_005114
NM_001005762
NP_001005762
NW_047454
AAC09244
AAD32304
AAH04314
AAH10146
AAH67260
AAH91514
AF037261
AF064807
BC004314
BC010146
BC067260
BC091514
CR598111
CR605936
CR606865
CR610210
CR621670
CR622445
CR623414
NC_000008
NM_001018003
NM_005775
NP_001018003
NP_005766
NT_023666
NT_086740
O60504
NM_011366
NP_035496
NT_039606
Q9R1Z8
U58889
AAC52642
AAD32303
AAH30933
AB190911
AF064806
AK029703
AK164607
AK165689
AK185985
AK197856
BAD91315

Chromosome position 14 34.5 cM
8p21.3
15p11

GO ID 0005200
0005515
0007155
0015629
0005856

Alias Sh3d4
vinexin
vinexin beta (SH3-containing adaptor molecule-1)
vinexin beta
SCAM I
SH3P3
vinexin alpha
SCAM-1
vinexin-g
vinexins
mgc94509
SH3 domain protein IV
SH3 domain protein 4

Organism Homo sapiens
Rattus norvegicus
Mus musculus

MedLine Reference 9885244
9630982

LocusLink ID 282843
10174
26990
20410

FunctionalClass protein binding
structural constituent of cytoskeleton

GO Cellular Component actin cytoskeleton
cytoskeleton

Cell Localization Cytoplasm

Pathway AR
ERalpha
GR

GO Biological Process cell adhesion

Group Cytoskeleton

Source Curated