| Name | DAXX |
|---|---|
| Description | Fas death domain-associated protein |
| Owner | Public |
| URN | urn:agi-llid:1616 |
| Connectivity | 64 |
| Notes | SUMMARY: mouse homolog acts as a transcriptional repressor and plays a role in apoptosis [RGD] |
| Hugo ID | 2681 |
| Microarray ID | af006040_s_at |
|---|---|
| A_51_P412835 | |
| 216038_x_at | |
| 41161_at | |
| 201763_s_at | |
| 1754_at | |
| AF006041_at | |
| rc_t79477_s_at | |
| A_32_P325977 | |
| A_32_P851696 | |
| A_23_P122579 | |
| A_14_P122500 | |
| A_14_P100360 | |
| aa684879_at | |
| 1387800_at | |
| A_42_P622574 | |
| 1419026_at | |
| 96125_at | |
| C234 | |
| OH8044 |
| Chromosome position | 17 17.0 cM |
|---|---|
| 6p21.3 | |
| 20p12 |
| GO ID | 0005871 |
|---|---|
| 0019904 | |
| 0005515 | |
| 0006355 | |
| 0016564 | |
| 0016605 | |
| 0005057 | |
| 0005634 | |
| 0005737 | |
| 0006350 | |
| 0006915 | |
| 0007257 | |
| 0008625 | |
| 0030521 | |
| 0031072 | |
| 0045892 | |
| 0047485 | |
| 0050681 |
| Alias | Fas death domain-associated protein |
|---|---|
| Fas-binding protein Daxx | |
| BING2 | |
| Daxx | |
| EAP1/Daxx | |
| death-associated protein VI | |
| DAP6 | |
| death-associated protein 6 |
| Organism | Rattus norvegicus |
|---|---|
| Homo sapiens | |
| Mus musculus | |
| Human |
| MedLine Reference | 10970097 |
|---|---|
| 15572661 | |
| 9215629 | |
| 11971979 | |
| 12529400 |
| LocusLink ID | 140926 |
|---|---|
| 13163 | |
| 1616 |
| FunctionalClass | protein domain specific binding |
|---|---|
| androgen receptor binding | |
| heat shock protein binding | |
| protein N-terminus binding | |
| protein binding | |
| transcriptional repressor | |
| receptor signaling protein |
| RGD ID | 621227 |
|---|
| Hugo Symbol | DAXX |
|---|
| Unigene ID | Rn.870 |
|---|---|
| Mm.271809 | |
| Hs.336916 |
| KEGG pathway | MAPK signaling pathway |
|---|
| GO Cellular Component | kinesin complex |
|---|---|
| cytoplasm | |
| nucleus | |
| PML body |
| Cell Localization | Nucleus |
|---|
| Pathway | FAS signaling |
|---|---|
| Death receptor signaling | |
| MAPK signaling | |
| SAPK-JNK Signaling | |
| p38 Signaling | |
| TNFRSF6 -> TP53 signalling pathway | |
| TNFRSF6 -> HSF1 signalling pathway | |
| TNFRSF6 -> PML signalling pathway | |
| AR | |
| GR | |
| NR common regulators |
| GO Biological Process | activation of JNK |
|---|---|
| androgen receptor signaling pathway | |
| apoptosis | |
| induction of apoptosis via death domain receptors | |
| negative regulation of transcription, DNA-dependent | |
| transcription | |
| regulation of transcription, DNA-dependent |
| Group | Ph |
|---|---|
| Transcription factors |
| MGI ID | 1197015 |
|---|
| Swiss-Prot Accession | Q9UER7 |
|---|
| OMIM ID | 603186 |
|---|---|
| OMIM:603186 |
| Source | Curated |
|---|