| Name | GATA1 |
|---|---|
| Description | GATA binding protein 1 (globin transcription factor 1) |
| Owner | Public |
| URN | urn:agi-llid:2623 |
| Connectivity | 89 |
| Notes | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. |
| Hugo ID | 4170 |
| Microarray ID | d13518_at |
|---|---|
| A_42_P747349 | |
| 102654_at | |
| 1449232_at | |
| 161456_f_at | |
| x15763_s_at | |
| A_51_P318168 | |
| A_52_P670095 | |
| X17254 | |
| 36787_at | |
| 210446_at | |
| 1555590_a_at | |
| X17254_at | |
| A_23_P304464 | |
| A_14_P116627 | |
| A_24_P374244 | |
| OR3526 | |
| OH0964A | |
| ST093 | |
| MB671 | |
| 1368510_at |
| Chromosome position | X 1.9 cM |
|---|---|
| Xq12 | |
| Xp11.23 |
| GO ID | 0005524 |
|---|---|
| 0003677 | |
| 0005515 | |
| 0006355 | |
| 0006357 | |
| 0007275 | |
| 0046872 | |
| 0003700 | |
| 0005634 | |
| 0006350 |
| Alias | GF I |
|---|---|
| GF1 | |
| 1190028F09 | |
| hypothetical gene supported by AK075701 | |
| hypothetical protein 1190028F09 | |
| Eryf1 | |
| GATA binding protein 1 | |
| GATA binding protein 1 (globin transcription factor 1) | |
| globin transcription factor 1 | |
| NFE1 | |
| globin transcription factor I | |
| Gata1 | |
| GATA binding protein I | |
| Gata I | |
| NFE I | |
| Eryf I |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MedLine Reference | 7957872 |
|---|---|
| 11724781 | |
| 12023274 | |
| 12496368 | |
| 15613485 | |
| 2104960 | |
| 2300555 | |
| 2467208 |
| LocusLink ID | 330481 |
|---|---|
| 25172 | |
| 14460 | |
| 2623 |
| FunctionalClass | ATP binding |
|---|---|
| protein binding | |
| DNA binding | |
| metal ion binding | |
| transcription factor |
| RGD ID | 2663 |
|---|
| Hugo Symbol | GATA1 |
|---|
| Unigene ID | Rn.10024 |
|---|---|
| Mm.335973 | |
| Hs.765 | |
| Mm.280913 |
| GO Cellular Component | nucleus |
|---|
| Cell Localization | Nucleus |
|---|
| Pathway | IL1 |
|---|---|
| BMP4-ACVR1 | |
| BMP4-BMPR1A | |
| BMP4-BMPR1B | |
| BMP4-BMPR2 | |
| IL3-CD8A | |
| IL3-CSF2RB2 | |
| IL3-EPOR | |
| IL3-IL3RA | |
| TGFB1-ACVR1 | |
| TGFB1-ACVR1B | |
| TGFB1-ACVR2 | |
| TGFB1-ACVR2B | |
| TGFB1-ACVRL1 | |
| TGFB1-BMPR1B | |
| TGFB1-CD44 | |
| TGFB1-IGF2R | |
| TGFB1-IL6R | |
| TGFB1-M6PR | |
| TGFB1-SELE | |
| TGFB1-SELL | |
| TGFB1-TGFBR1 | |
| TGFB1-TGFBR2 | |
| TGFB1-TGFBR3 | |
| ERalpha | |
| GR |
| GO Biological Process | development |
|---|---|
| regulation of transcription from RNA polymerase II promoter | |
| transcription | |
| regulation of transcription, DNA-dependent | |
| regulation of transcription from Pol II promoter |
| Group | Transcription factors |
|---|
| MGI ID | 95661 |
|---|
| Swiss-Prot Accession | P15976 |
|---|
| OMIM ID | 305371 |
|---|---|
| 300367 | |
| 190685 |
| Source | Curated |
|---|