Protein : Nr2f2

Name Nr2f2
Description nuclear receptor subfamily 2, group F, member 2
Owner Public
URN urn:agi-llid:7026
Connectivity 22
Notes COUP-TFII represses the alpha-subunit of mitochondrial F1F0 ATP synthase (ATPA) complex and inhibits the USF2-dependent transactivation of the ATPA promoter through competition for an overlapping bindng site in the ATPA cis-acting regulatory element 1. DAX-1 and COUP-TFII may play a role in the modulation of Ad4BP/SF-1-dependent transcription of steroidogenic enzymes in different cell types and follicular stages in normal cycling human ovaries. Transcription factor COUP 2 (chicken ovalbumin upstream promoter 2, apolipoprotein regulatory protein).

Microarray ID 1370063_at
1395863_at
rc_ai012183_at
A_43_P13085
103052_r_at
1416158_at
1416159_at
x76653_s_at
A_51_P147684
M64497 >b
M64497 >a
215073_s_at
39397_at
209119_x_at
209121_x_at
209120_at
242396_at
M64497_at
A_23_P88589
A_23_P422703
A_14_P110742
A_14_P137609
A_24_P313354
OR1656
OH12170
MA469

GenBank ID NM_009697
NM_183261
NP_033827
NP_899084
NT_039428
P43135
U07635
AAA21479
AAA86429
AAB09475
AAH14664
AAH42897
BC014664
BC033957
BC034585
BC042897
M62760
M64497
NC_000015
NM_021005
NP_066285
NT_010274
NT_086832
P24468
U60477
X76653
AAB61297
AF003944
NC_005100
NM_080778
NP_542956
NW_047560
O09018
AAH42484
AAA19854
AK012322
AK012573
AK032882
AK034619
AK140125
BAC25364
BAE24245
BC042484
BC094360
CAA54096
NC_000073

Chromosome position 15q26
1q31
7 33.0 cM

GO ID 0009956
0030900
0001764
0003677
0004872
0004879
0005667
0006355
0009952
0003700
0003706
0003707
0003714
0005634
0006350
0006357
0006629
0007165
0046872

Alias apolipoprotein regulatory protein
Aporp1
COUP transcription factor 2
COUP-TF2
COUPTFB
COUP-TFII
Nr2f2
nuclear receptor subfamily 2, group F, member 2
Tcfcoup2
TFCOUP2
RIKEN cDNA 9430015G03 gene
9430015G03Rik
COUP transcription factor II
transcription factor COUP 2 (chicken ovalbumin upstream promoter 2, apolipo
COUP-TF II
SVP40
Aporp I
Aporp Is
Aporp1s
COUPTFBs
transcription factor coup II
transcription factor coup 2
Apolipoprotein AI regulatory protein-1
Apolipoprotein AI regulatory protein I

Organism Homo sapiens
Rattus norvegicus
Mus musculus

MedLine Reference 15548577
15829524
1899293
8530078

LocusLink ID 67192
113984
11819
320677
7026

FunctionalClass DNA binding
ligand-dependent nuclear receptor
receptor
ligand-regulated transcription factor
metal ion binding
steroid hormone receptor
transcription corepressor
transcription factor

GO Cellular Component nucleus
transcription factor complex

Cell Localization Plasma membrane
Nucleus

Pathway PPAR all
PPARalpha
GR
COUP-TF
HNF4a
NR common targets
NR common regulators
NR CYP ABCs
NR target genes

GO Biological Process lipid metabolism
regulation of transcription from RNA polymerase II promoter
signal transduction
transcription
anterior/posterior pattern formation
forebrain development
neuron migration
radial pattern formation
regulation of transcription, DNA-dependent

Group Nuclear receptors
Nrs

Source Curated