| Entities | NR3C1 ---- GSR |
|---|---|
| References | 6 |
| Connectivity | 2 |
| Effect | unknown |
| Owner | Public |
| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:2936:inout-urn:agi-llid:2908::unknown |
| Organ | liver |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v274 i9 p5880 (1999) |
| Journal Link | http://www.jbc.org/cgi/content/full/274/9/5880 |
| MedLine Reference | 10026211:1027 |
| Sentence | This unit consists of (from 5' to 3') two accessory factor elements (AF1 and AF2), two glucocorticoid receptor-binding sites (GR1 and GR2), a third accessory element (AF3), and the cyclic AMP response element (CRE ) (see Fig. 1 ). |
| Organism | Rattus norvegicus |
| Journal | J. Biol. Chem |
|---|---|
| Journal Reference | v276 i25 p22675 (2001) |
| Journal Link | http://www.jbc.org/cgi/content/full/276/25/22675 |
| MedLine Reference | 11309401:1035 |
| Sentence | The GRU includes a linear array of three accessory factor-binding sites, AF1 (-451 to -439), AF2 (-416 to -407), and AF3 (-326 to -321), and two glucocorticoid receptor-binding sites, GR1 and GR2 (-386 to -353) ( 15 ). |
| Organism | Mus musculus |
| MedLine Reference | 8058068:1 |
|---|---|
| Sentence | The glucocorticoid response is mediated by a complex regulatory unit that consists of two glucocorticoid receptor (GR) binding sites (GR1 and GR2) and two adjacent accessory factor elements (AF1 and AF2). |
| Organism | Rattus norvegicus |
| Organ | liver |
|---|---|
| MedLine Reference | 8813720:1 |
| Sentence | The glucocorticoid response is mediated by a complex glucocorticoid response unit that consists of two glucocorticoid receptor (GR)-binding sites (GR1 and GR2) and two accessory factor-binding sites (AF1 and AF2). |
| Organism | Rattus norvegicus |
| MedLine Reference | 9773973:0 |
|---|---|
| Sentence | The phosphoenolpyruvate carboxykinase (PEPCK) gene promoter contains a glucocorticoid response unit (GRU) that includes three accessory factor-binding sites (AF1, AF2, and AF3), two glucocorticoid receptor-binding sites (GR1 and GR2), and a cAMP response element. |
| Organism | Rattus norvegicus |
| Organ | liver |
|---|---|
| Journal | Mol. Endocrin |
| Journal Reference | v13 i4 p604 (1999) |
| Journal Link | http://mend.endojournals.org/cgi/content/full/13/4/604 |
| MedLine Reference | 10194766:1016 |
| Sentence | The GRU consists of two adjacent glucocorticoid receptor (GR)-binding sites (GR1 and GR2) and four accessory elements: AF1, AF2, AF3, and the cAMP response element (CRE) (see Fig. 1 ) ( 6 , 7 , 8 ). |