| Entities | NR3C1 ---- GNRH1 |
|---|---|
| References | 3 |
| Connectivity | 2 |
| Effect | unknown |
| Owner | Public |
| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:2908:inout-urn:agi-llid:2796::unknown |
| Journal | Mol. Endocrin |
|---|---|
| Journal Reference | v14 i9 p1509 (2000) |
| Journal Link | http://mend.endojournals.org/cgi/content/full/14/9/1509 |
| MedLine Reference | 10976927:1247 |
| Sentence | Furthermore, the glucocorticoid receptor binds to the 5'-region of FP2 in the equivalent area in the mouse GnRH promoter ( 29 ). |
| Organism | Rattus norvegicus |
| CellType | neural |
|---|---|
| Tissue | gonad |
| Organ | brain |
| Journal | J. Biol. Chem |
| Journal Reference | v271 i34 p20412 (1996) |
| Journal Link | http://www.jbc.org/cgi/content/full/271/34/20412 |
| MedLine Reference | 8702778:1031 |
| Sentence | Recently Ahima and Harlan ( 21 ) demonstrated that a subset of GnRH neurons in the rat brain contain immunoreactive GR, raising the possibility that genomic effects of GR within these neurons could directly influence GnRH gene expression and secretion and thus the hypothalamic-pituitary-gonadal axis. |
| Organism | Mus musculus |
| CellLineName | GT1 |
|---|---|
| Journal | Endocrinology |
| Journal Reference | v140 i11 p5045 (1999) |
| Journal Link | http://endo.endojournals.org/cgi/content/full/140/11/5045 |
| MedLine Reference | 10537130:1030 |
| Sentence | Glucocorticoid receptor-mediated repression of GnRH promoter activity has been demonstrated in GT1 cells ( 15 ). |
| Organism | Rattus norvegicus |