| Entities | GRLF1 ---- NR3C1 |
|---|---|
| References | 2 |
| Connectivity | 2 |
| Effect | unknown |
| Owner | Public |
| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:2909:inout-urn:agi-llid:2908::unknown |
| MedLine Reference | 1894621:0 |
|---|---|
| Sentence | The human DNA binding factor GRF-1, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. |
| Organism | Rattus norvegicus |
| CellLineName | VENTRAL |
|---|---|
| Tissue | epithelia |
| Organ | prostate |
| Journal | Endocrinology |
| Journal Reference | v140 i7 p3328 (1999) |
| Journal Link | http://endo.endojournals.org/cgi/content/full/140/7/3328 |
| MedLine Reference | 10385430:1125 |
| Sentence | Two members of the p190 family have been described to date ( 24 , 26 ). p190A mRNA is a ubiquitous mRNA, approximately 8.3 kb in size, which has significant sequence homology to GRF-1, a 95-kDa protein that is a transcriptional repressor of the glucocorticoid receptor gene ( 27 ). p190B appears to be encoded by a transcript of 6.4 kb, and the gene product has 51% amino acid homology to p190A ( 24 ). |
| Organism | Rattus norvegicus |