| Entities | HSPA1A ---- NR3C1 |
|---|---|
| References | 3 |
| Connectivity | 2 |
| Effect | unknown |
| Owner | Public |
| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:3303:inout-urn:agi-llid:2908::unknown |
| Journal | Mol. Endocrin |
|---|---|
| Journal Reference | v18 i3 p500 (2004) |
| Journal Link | http://mend.endojournals.org/cgi/content/full/18/3/500 |
| MedLine Reference | 14673132:1144 |
| Sentence | To explain the role of GR in this response, we reasoned that it might occur by displacement of HSF1 through binding of GR to the Hsp70 promoter. |
| Organism | Mus musculus |
| CellType | hepatocyte |
|---|---|
| CellLineName | GR |
| Journal | Reg.Int.Comp.Phys |
| Journal Reference | v283 i3 pR680 (2002) |
| Journal Link | http://ajpregu.physiology.org/cgi/content/full/283/3/R680 |
| MedLine Reference | 12185003:1158 |
| Sentence | Also, heat shock, even in the absence of cortisol, downregulates GR in trout hepatocytes, but this decreased GR correlated with elevated hsp70 content ( 4 ). |
| Journal | EMBO |
|---|---|
| Journal Reference | v19 i23 p6508 (2000) |
| Journal Link | http://embojournal.npgjournals.com/cgi/content/full/19/23/6508 |
| MedLine Reference | 11101523:1186 |
| Sentence | The liganded GR transports both Hsp70/Hsc70 and RAP46 into the nucleus, where RAP46 uses its N-terminal sequence in a process that is not fully understood to downregulate transactivation by the GR. |