| Transport Type | unknown |
|---|---|
| Owner | Public |
| URN | urn:agi-MolTransport:inout-urn:agi-cas:50-22-6:out-urn:agi-llid:2908: |
| Entities | corticosterone ---> NR3C1 |
| References | 8 |
| Connectivity | 2 |
| Organism | Rattus norvegicus |
|---|---|
| MedLine Reference | 2226278:9 |
| Sentence | On the other hand, a single dose of corticosterone (100 micrograms/100 g) as well as long-term corticosterone treatment (100 micrograms/ml saline as drinking solution for 6 days) reduced the glucocorticoid receptor concentration only to 60% and 25%, respectively. |
| Organism | Rattus norvegicus |
|---|---|
| Organ | hippocampal |
| MedLine Reference | 9483579:11 |
| Sentence | A new intracellular environment rather than excessive serum corticosterone caused by CVS may contribute to inhibition of the formation of GR-HSP complex. |
| Tissue | testis |
|---|---|
| Organism | Rattus norvegicus |
| MedLine Reference | 7594229:7 |
| Sentence | On the other hand, adrenalectomy or repeated corticosterone treatment seem to affect GR similarly in all positive cells without changing significantly the proportion of GR IR in the different testicular compartments. |
| Organism | Rattus norvegicus |
|---|---|
| Organ | hippocampal |
| MedLine Reference | 3986609:8 |
| Sentence | In adults corticosterone treatment decreased (-45%) and long-term adrenalectomy increased (211%) glucocorticoid receptor concentrations. |
| Tissue | epithelia |
|---|---|
| Organism | Rattus norvegicus |
| Organ | liver |
| MedLine Reference | 10467229:6 |
| Sentence | In this study corticosterone and dexamethasone treatments increased the number of AT1 receptors by activating the glucocorticoid receptor (GR). |
| CellLineName | WB |
| Organ | hippocampal |
|---|---|
| MedLine Reference | 2300131527 |
| Sentence | Thus, in the hippocampus, this one compound, CORT, serves to regulate the two signaling pathways via the MR and GR (Reul and de Kloet, 1985 ; Pearce and Yamamoto, 1993 ; Kawata, 1995 ). |
| Organism | Rattus norvegicus |
|---|---|
| MedLine Reference | 1660971:0 |
| CellType | neural |
| Sentence | Corticosterone can affect electrical properties of CA1 pyramidal neurons via binding to two corticoid receptor types, the mineralocorticoid (MR) and glucocorticoid receptor (GR). |
| Tissue | nerve |
|---|---|
| Organism | Rattus norvegicus |
| MedLine Reference | 4042964:6 |
| Sentence | Upon acute corticosterone treatment of adrenalectomized male rats, the GR immunoreactivity was again mainly demonstrated in the nerve cell nuclei indicating that corticosterone can translocate GR from the cytoplasm to the cell nuclei. |