| Owner | Public |
|---|---|
| URN | urn:agi-Binding:inout-urn:agi-llid:2908:inout-urn:agi-llid:10499: |
| Entities | NCOA2 ---- NR3C1 |
| References | 5 |
| Connectivity | 2 |
| Journal | EMBO |
|---|---|
| Journal Reference | v20 i21 p6071 (2001) |
| Journal Link | http://embojournal.npgjournals.com/cgi/content/full/20/21/6071 |
| MedLine Reference | 11689447:1113 |
| Sentence | TIF2/GRIP1 associates with GR at the col 3A element in vivo |
| Organism | Mus musculus |
| MedLine Reference | 12748280:4 |
|---|---|
| CellLineName | T47D |
| Sentence | In contrast, activated glucocorticoid receptor (GR) preferentially associated with SRC-2 (TIF-2/GRIP-1), which subsequently recruited pCAF and led to specific modification of histone H3, suggesting that specific coactivators recruit distinct histone acetyltransferases to modulate the transcription of steroid-responsive genes. |
| Organism | Mus musculus |
| Tissue | mammary |
| Journal | Mol. Cell. Biol |
|---|---|
| Journal Reference | v25 i1 p264 (2005) |
| Journal Link | http://mcb.asm.org/cgi/content/full/25/1/264 |
| MedLine Reference | 15601848:1339 |
| Sentence | One key difference between GR- and PR-dependent induction of MMTV activity is that GR recruits TIF2/GRIP1 rather than SRC-1 to the MMTV promoter in T47D Cat0 cells ( 28 ). |
| Tissue | mammary |
| Journal | Mol. Endocrin |
|---|---|
| Journal Reference | v17 i9 p1681 (2003) |
| Journal Link | http://mend.endojournals.org/cgi/content/full/17/9/1681 |
| MedLine Reference | 12805412:1227 |
| Sentence | In contrast, GR interacts preferentially with SRC-2, which recruits p/CAF and results in histone H3 acetylation. |
| MedLine Reference | 15207724:3 |
|---|---|
| Sentence | Both endogenously and ectopically expressed TIF2 were shown to form foci in the nucleus, and GR could be recruited to the TIF2 foci upon GR agonist but not antagonist treatment. |