| Name | KNG |
|---|---|
| Description | kininogen 1 |
| Owner | Public |
| URN | urn:agi-llid:3827 |
| Connectivity | 86 |
| Notes | SUMMARY: precursor protein of kinin which is found in plasma; cysteine protease inhibitor and a major acute phase reactant [RGD] |
| Hugo ID | 6383 |
| Microarray ID | k02814_at |
|---|---|
| 1387050_s_at | |
| k02814_g_at | |
| 1416676_at | |
| 93837_at | |
| A_51_P451377 | |
| 217512_at | |
| 243562_at | |
| 37235_g_at | |
| 37234_at | |
| 56482_at | |
| 89933_at | |
| 206054_at | |
| 37236_at | |
| M11437_cds1_at | |
| M11437_cds2_at | |
| rc_t23882_s_at | |
| A_23_P212258 | |
| A_14_P138044 | |
| A_24_P60381 | |
| OH1774 | |
| RT216 | |
| OR3824 | |
| H185 |
| Chromosome position | 3q27 |
|---|---|
| 11q23 | |
| 16 B1 |
| GO ID | 0005515 |
|---|---|
| 0005576 | |
| 0004866 | |
| 0050880 | |
| 0008217 | |
| 0043065 | |
| 0004869 | |
| 0005102 | |
| 0005615 | |
| 0006939 | |
| 0006954 | |
| 0007162 | |
| 0007596 | |
| 0008201 | |
| 0008270 | |
| 0030146 | |
| 0030147 | |
| 0030195 | |
| 0042311 |
| Alias | similar to alpha-1 major acute phase protein prepeptide |
|---|---|
| Kng | |
| Kng_v Is | |
| Kng_v1s | |
| mgc108747 | |
| Kng_v1 | |
| kininogen 1 | |
| kininogen I | |
| KNG1 | |
| T-kininogen | |
| Alpha-2-thiol proteinase inhibitor | |
| H-kininigen | |
| kininogen | |
| KINT1G | |
| Kngt | |
| Kngt1 | |
| L-kininogen | |
| Kngk | |
| RATKINKH | |
| K-kininogen, differential splicing leads to HMW Kngk | |
| RATKINT1G | |
| see also D11Elh1 and D11Mit | |
| alpha-1 major acute phase protein prepeptide | |
| KINKH | |
| bradykinin | |
| RATTKG6 | |
| T-kininogen, see also D11Elh1 and D11Mit8 | |
| Kngt I | |
| KINKG | |
| RATKINKG | |
| Kng_v I | |
| TKG6 |
| Organism | Homo sapiens |
|---|---|
| Rattus norvegicus | |
| Mus musculus |
| MedLine Reference | 12466851 |
|---|---|
| 11290596 | |
| 11385996 | |
| 11970955 | |
| 12715893 | |
| 12911595 |
| LocusLink ID | 24903 |
|---|---|
| 246369 | |
| 16644 | |
| 25087 | |
| 288001 | |
| 589 | |
| 3827 |
| FunctionalClass | endopeptidase inhibitor |
|---|---|
| cysteine protease inhibitor | |
| heparin binding | |
| receptor binding | |
| zinc ion binding |
| RGD ID | 2980 |
|---|
| Hugo Symbol | KNG1 |
|---|
| Unigene ID | Hs.77741 |
|---|---|
| Mm.2160 | |
| Rn.44576 |
| KEGG pathway | Complement and coagulation cascades |
|---|
| GO Cellular Component | extracellular region |
|---|---|
| extracellular space |
| Cell Localization | Extracellular |
|---|---|
| Cytoplasm |
| Pathway | F2-ITGAV |
|---|---|
| F2-LRP1 | |
| F2-LRP2 | |
| Volcano 2 | |
| Ben Common regulators | |
| FXR |
| GO Biological Process | blood coagulation |
|---|---|
| diuresis | |
| inflammatory response | |
| natriuresis | |
| negative regulation of blood coagulation | |
| negative regulation of cell adhesion | |
| positive regulation of apoptosis | |
| smooth muscle contraction | |
| vasodilation | |
| regulation of blood pressure | |
| regulation of blood vessel size |
| MGI ID | 1097705 |
|---|
| Swiss-Prot Accession | P01042 |
|---|
| OMIM ID | 228960 |
|---|
| Source | Curated |
|---|